Takaysu arteritis treatment in children

نویسندگان

  • YO Kostina
  • GA Lyskina
چکیده

Methods Group 1 (36 patients) received the combined therapy by glucocorticoids (Pr) and methotrexate (MTX). Cyclophosphamide (CYC) used at 2 patients as first therapy with widespread inflammation and in 6 – at inefficiency of primary treatment of MTX (group 2). In 5 children with refractory TA – infliximab (INF) (group 3). TR efficacy was estimated by TA activity index (AI), based on Birmingham scale of vasculitis activity (erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), clinical symptoms and results of Doppler ultrasound, etc.).

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Histopathologic Features of Giant Cell Arteritis in an Actinic Granuloma Lesion

The association between actinic granuloma and giant cell arteritis (temporal arteritis) has been claimed by some authors. There is a hypothesis that actinic radiation has the principal role in the etiology of both diseases in a similar way. Here, we report a case of actinic granuloma that had characteristic pathologic features of giant cell arteritis in histopathologic examination without clini...

متن کامل

Magnetic resonance imaging in the diagnosis and follow up of Takayasu's arteritis in children.

BACKGROUND Takayasu's arteritis (TA) has a mortality rate of up to 40% in children. Because the clinical presentation of TA is often non-specific, accurate and prompt diagnosis depends on a high degree of awareness and appropriate laboratory and imaging studies. OBJECTIVE To examine the use of advanced magnetic resonance imaging (MRI) in evaluating, gauging activity, and following the complic...

متن کامل

Evaluation of Serum CRP and Vitamin D in Rheumatoid Arteritis Patients and Healthy People

Abstract Background and Objective: C- reactive protein (CRP), as an acute phase reactant and a reliable marker of inflammation, increases due to inflammatory diseases such as Rheumatoid Arteritis and infectious conditions. New evidence shows that Vitamin D may have important effects on adjusting and reducing the Immune Responses. The aim of this study was to evaluate the association between...

متن کامل

Review Takayasu arteritis in children and adolescents

Takayasu arteritis is a devastating vasculitis of the aorta and its major branches. The clinical manifestations in paediatric patients are less specific than in adults: in children the disease presents with fever, arthralgias and hypertension. Intramural inflammation results in narrowing of the blood vessel lumen and therefore hypoperfusion of the parenchyma. Conventional angiography is the gol...

متن کامل

Takayasu arteritis presenting as cerebral aneurysms in an 18 month old: A case report

BACKGROUND Central nervous system involvement occurs in as many as twenty percent of Takayasu arteritis cases. When central nervous system disease is present, it typically manifests as cerebral ischemia or stroke. There are rare reports of intracranial aneurysms in adults with Takayasu arteritis, but none in children. CASE PRESENTATION We describe a case of Takayasu arteritis in an 18 month o...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 12  شماره 

صفحات  -

تاریخ انتشار 2014